Jones – Cardiac Structure and Function

Our group's goal is to know the cellular composition of the heart during disease and across lifespan. We will apply such information to elucidating the causes and consequences of cardiac health and disease. In all such endeavors, the laboratory invokes a multidisciplinary approach to answer important questions in a variety of in vivo and in vitro models supported by our Center. Our group also provides a fertile environment for trainees to gain the necessary experience and guidance to become independent investigators.

Who We Are

We are a collaborative group of experienced staff members and energetic trainees. Go here to explore our team. The group is led by Dr. Steven Jones, who is an established expert in ventricular remodeling and integrative physiology.

What We Do

We have a long history of NIH and AHA funding to support our work. We engage a host of modern techniques to uncover the mysteries of the cardiovascular system. Go here to see our areas of interest.

Feb 25, 2025

Kudos to Danielle Little (pictured at right) on the first paper from her thesis work. In this paper, she shows that cardiac fibroblasts are a primary source for the metabolism-derived signal, hyaluronan, which is primarily produced by the enzyme HAS2.

Jan 1, 2025

Cait Howard started her American Heart Association Predoctoral Fellowship today. During her fellowship, she will address how a metabolic signal (hyaluronan) impacts inflammation after a heart attack. Congrats, Cait! (she is pictured at right)

Dec 23, 2024

Congratulations to Tim Audam and Cait Howard on their co-first author paper in JMCC! Cait's picture is above; Dr. Audam is pictured at right. Dr. Audam is currently a postdoctoral fellow at the Broad Institute.

Publications

For a complete list, please visit our Publications Page.

Contact

Steven P Jones, PhD, FAHA

Professor and Director, Center for Cardiometabolic Science

Steven.P.Jones AT Louisville.edu

Center for Cardiometabolic Science

University of Louisville

Cardiac Structure and Function Laboratory

What Makes Us Beat

Who We Are

What We Do

Publications

Contact

Steven P Jones, PhD, FAHA